簡要描述:英文名稱: BIO (2’Z,3’E)-6-Bromoindirubin-3-oxime產(chǎn)品應(yīng)用: WNT信號通路抑制劑中國俗稱: GSK3激酶抑制劑 注冊品牌: StemRD 生產(chǎn)廠家: 美國StemRD公司訂購貨號: BIO-005規(guī)格型號: 5mg保存溫度: ﹣20℃產(chǎn)品種類: 小分子工具到貨時間: 1~5天
產(chǎn)品目錄
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產(chǎn)品英文名稱: BIO (2’Z,3’E)-6-Bromoindirubin-3-oxime
產(chǎn)品中文名稱: BIO (2’Z,3’E)-6-Bromoindirubin-3-oxime
訂購:
BIO 產(chǎn)品英文簡述:
BIO (6-bromoindirubin-3'-oxime) is a specific GSK3 kinase inhibitor. Inhibition of GSK3-beta results in activation of the canonical WNT pathway leading to the translocation of beta-catenin to the nucleus.
This chemical compound from StemRD is 98.5% pure (HPLC). In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 5.0 micromolar.
Purity: Greater than 98.5% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.
Biological Activity: In a cell-based assay measuring the activation of the TCF reporter gene, this compound gives EC50 of 5.0 micromolr.
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